La-Mulana (InstanceTopic, 17)

From Compile Worlds

La-Mulana is an indie game created as an homage to the MSX computer system. It is an epic Indiana Jones-style adventure through 20 massive gameplay areas, organized into pairs (well, okay, there's only 19 if you count the Twin Labyrinths as one area, but it's still huge). It is comparable to Cave Story in many ways, including the quality of its graphics and music, the depth of the storyline, the complexity of the gameplay, how seamless the game is as a whole, and how they both got a WiiWare port with even better graphics and music.