Ai to Yuuki to Kashiwa Mochi (InstanceTopic, 18)
From Compile Worlds
Ai to Yuuki to Kashiwa Mochi is a puzzle game similar to Bejeweled Twist, just with bidirectional rotation, diagonal matches, and you have to get four in a row instead of three, and it has sweets instead of jewels, and it doesn't have all the neat special effects...
It stars a girl named Ai-chan and her friend Yuuki, adventuring through a brown-orange dreamland filled with the aforementioned sweets.
So you'd think it was a nice innocent, casual, relaxing game to try out once in a while... until you realize it was made by the same guy who made Irisu Syndrome, and has a page on DarthWiki.